Letter to the Editor December 15, 1996

Nefazodone and Symptoms Suggesting Neurotoxicity: A Case Report

Talia Puzantian; Richard J. Shaw

J Clin Psychiatry 1996;57(12):595

Article Abstract

Letter to the Editor

Sir: We report a case of reversible neurotoxicity possibly induced
by an increase in the dose of nefazodone.

Case report. Mr. A, a 43-year-old man with schizoaffective
disorder, presented with complaints of paranoid ideation, auditory
hallucinations, and suicidal ideation. One week prior to admission,
he had discontinued his regularly prescribed medications,
which included sertraline, risperidone, diazepam, cyclobenzaprine,
and carbamazepine.