Article July 31, 2000

Optimizing Lithium Treatment

David L. Dunner, MD

J Clin Psychiatry 2000;61(suppl 9):76-81

Article Abstract

The purpose of this article is to discuss treatment of side effects that can occur during lithiumtherapy. Side effects from lithium are common but generally benign. For this article, I have dividedthe side effects into those that occur early, those that are late appearing, side effects related to druginteractions, and lithium toxicity. Side effects can decrease compliance. Lithium is a very effectivedrug for the stabilization of mood disorder in bipolar patients. Since side effects can affect compliance,recognition and treatment of early and late-appearing side effects are important aspects of lithiumpharmacotherapy.