Article March 1, 1998

Overcoming Treatment Resistance in Depression

J. Craig Nelson, M.D.

J Clin Psychiatry 1998;59(suppl 16):13-19

Article Abstract

Treatment-resistant depression is commonly encountered by mental health professionals. Strategiesfor the treatment of resistant depression, including augmentation strategies and switching antidepressants,are reviewed. The potential advantages and disadvantages of each of these strategies arediscussed.