The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Solriamfetol for ADHD in Adults
Original Research

October 9, 2023

Some individuals with attention-deficit/hyperactivity disorder (ADHD) may not tolerate or adequately respond to currently available treatments. This study examined the efficacy and tolerability of solriamfetol in the treatment for…
Craig B. H. Surman, Daniel M. Walsh, Nora Horick, et al
JCP
Celecoxib Augmentation of Vortioxetine for Cognition in MDD
Original Research

October 4, 2023

Anti-inflammatory augmentation of vortioxetine did not provide additional benefit in reducing cognitive symptoms of MDD.
Emma Sampson, Natalie T. Mills, Hikaru Hori, et al
JCP
Physical Exercise and Health, 1: Terminology, Guidance, Benefits, and Risks
Clinical and Practical Psychopharmacology

October 4, 2023

This article outlines current evidence and guidance for clinicians on encouraging physical activity in their patients.
Chittaranjan Andrade
JCP
Lemborexant and Daridorexant in Insomnia: NNT, NNH, and LHH
Original Research

October 2, 2023

This study examined whether differences existed between lemborexant and daridorexant in number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped or harmed (LHH)…
Leslie Citrome, Timothy R. Juday, Christie Lundwall
JCP
Dual Orexin Receptor Antagonists and Suicide Risk
Brief Report

September 27, 2023

According to the WHO pharmacovigilance database, suicidal behavior was 1.3 times more frequent than expected with dual orexin receptor antagonists and 4.7 times more frequent for Z-drugs; data on…
Francesco Salvo, Laura Palagini, Pierre A. Geoffroy
JCP
Earlier Use of Paliperidone Palmitate in Patients With Schizophrenia
Original Research

September 25, 2023

Long-acting injectable antipsychotics (LAIs) are typically reserved for patients with a long history of schizophrenia. This analysis of 3 studies found benefit in initiating the LAI paliperidone palmitate earlier…
Oliver J. Lopena, Larry D. Alphs, Martha Sajatovic, et al
JCP
Amyotrophic Lateral Sclerosis and Suicide Attempts
Original Research

September 20, 2023

The common risk factors for suicide attempts may not directly apply to patients with amyotrophic lateral sclerosis (ALS) due to their group-specific characteristics. This study aimed to identify risk…
Hyung Keun Park, Seok-Jin Choi, Ye-Jee Kim, et al
JCP
Optimizing Women's Health: Mood Disorders Through Lifespan
Academic Highlights

September 18, 2023

Mood disorders throughout women’s reproductive stages require comprehensive care to alleviate unnecessary suffering, comorbidities, and unwanted outcomes.
Kathryn M. Abel, Marlene P. Freeman
JCP
THC for Neuropsychiatric Symptoms of Dementia
Original Research

September 18, 2023

Neuropsychiatric symptoms (NPS) in dementia are challenging to manage, and available treatments have a significant side effect profile. This study evaluated the effectiveness of dispensary-obtained tetrahydrocannabinol for patients with…
Samantha M. Sawicki, Cristian Hernandez, Neda Laiteerapong, et al
JCP
Excess Mortality Associated With Schizophrenia
Original Research

September 13, 2023

Females, patients with connective tissue disorders, and those aged 20 years or younger were especially impacted by the effect of schizophrenia on increasing mortality.
Chih-Ming Cheng, Wen-Han Chang, Shih-Jen Tsai, et al
JCP
Coprescribing of Z-Drugs and Opioids During COVID-19
Original Research

September 11, 2023

Coprescribing of nonbenzodiazepine sedative-hypnotics, or “Z-drugs,” with opioids was more common among older patients, although the odds of coprescription among patients overall decreased over the COVID-19 lockdown period.
Akhil Anand, Jeremy Weleff, Nicolas R. Thompson, et al
JCP
Mortality Within 1 Year After Suicide Attempt
Original Research

September 11, 2023

One in 100 people who attempted suicide died by suicide within 1 year; men aged 45 years or older were at greater risk than other demographic groups.
Alice Demesmaeker, Ali Amad, Emmanuel Chazard, et al

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