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JCP
Pharmacokinetics of Olanzapine Intranasal Spray vs Olanzapine IM
Original Research

March 19, 2025

Two investigational intranasal formulations of olanzapine containing the permeation enhancer dodecyl maltoside showed favorable pharmacokinetics and an acceptable safety profile in healthy adults.
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JCP
Discordant Sibling Pair Comparisons
Clinical and Practical Psychopharmacology

March 17, 2025

Illustrative examples are used to explain what sibling studies are and how sibling comparisons can strengthen or weaken causal hypotheses in observational studies.
JCP
Negative Ethnic-Racial Identity and Internalizing Symptoms in Latiné Youth Exposed to Trauma
Original Research

March 17, 2025

In a large group of Latiné youth who had experienced trauma, negative affect about their ethnic racial identity not only was associated with worse internalizing symptoms, but also increased…
, , , et al
JCP
Suicide and Benzodiazepine Use in Veterans With Bipolar Disorder
Original Research

March 12, 2025

Among VHA patients diagnosed with bipolar disorder, receipt of a benzodiazepine prescription of ≥ 30 days was associated with increased suicide risk, even after controlling for clinical and demographic…
, , , et al
JCP
Eating Disorders Among Transgender and Gender Diverse People: Qualitative Analysis of Reddit Threads
Commentary

March 10, 2025

This subreddit analysis characterizes the body dissatisfaction and desire to eliminate gendered physical characteristics that transgender and gender diverse (TGD) people with eating disorders experience. Many on the subreddit…
, ,
JCP
Plasma Biomarkers and Incident Mild Behavioral Impairment
Original Research

March 5, 2025

High baseline plasma p-tau181 levels were associated with a greater risk of incident mild behavioral impairment in multi-ethnic Asian older adults with mixed pathology over a 5-year period.
, , , et al
JCP
Incidence and Risk Factors for Suicide Attempt During Pregnancy and Postpartum
Original Research

March 5, 2025

Risks of a postpartum suicide attempt were increased 4- to 30-fold by clinical factors, including prenatal suicide attempt ED visits, psychiatric ED visits, and assault ED visits, and by…
, , , et al
JCP
A New Tool to Refine Lithium Therapy: Simple Formula for a Complex Problem
Commentary

March 3, 2025

The authors consider potential benefits and limitations of a new equation for estimating 12-hour serum lithium levels.
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JCP
Maintenance of Antidepressant Effect After 1 Dose of Psilocybin
Original Research

March 3, 2025

Over 52 weeks, a single administration of 25 mg psilocybin suggested longer maintenance of antidepressant effect than both 1 mg and 10 mg.
, , , et al
JCP
Estimating the 12-Hour Serum Lithium Level
Original Research

March 3, 2025

Lithium blood tests should be conducted 12 hours after the last lithium dose, but complying with this strict timing is difficult. The authors developed a simple tool to estimate…
, , , et al
JCP
Back to the Office: The Room Where It Happens?
Commentary

March 3, 2025

The authors discuss in-person versus remote delivery of psychotherapy and present the findings of a survey characterizing current practice.
, , , et al
JCP
Xanomeline-Trospium Tolerability: Commentary
Commentary

February 26, 2025

The author discusses new findings from Kaul et al on the safety and tolerability of xanomeline-trospium.

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