The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
SPRAVATO® (esketamine) CIII Nasal Spray: The First and Only N-Methyl D-Aspartate (NMDA) Receptor Antagonist Approved in Conjunction With an Oral Antidepressant for the Treatment of Adults With Treatment-Resistant Depression
Information from Industry

June 30, 2020

JCP
Brief Report

June 30, 2020

This case series investigates the potential for nitrous oxide to rapidly reduce symptoms of posttraumatic stress disorder. Did it help the 3 Veteran outpatients who received it? Read this…
Andrea Varias, Peter van Roessel, Maryam Parsiani, et al
JCP
Original Research

June 30, 2020

Aside from intramuscular injection, few rapidly acting pharmacotherapeutic treatments are available for acute agitation. This study examined the safety and tolerability of INP105, a drug-device combination product that allows…
Stephen B. Shrewsbury, Jasna Hocevar-Trnka, Kelsey H. Satterly, et al
JCP
Academic Highlights

June 30, 2020

In this journal CME activity, find experts’ recommendations for reducing schizophrenia relapse, such as adopting a patient-centered approach, selecting medications based on current evidence, and implementing psychosocial interventions.
Christoph U. Correll, John Lauriello
JCP
Original Research

June 23, 2020

Can comorbid posttraumatic disorder (PTSD) affect treatment of depression? This study compared 3 next-step treatment options in veterans who had major depressive disorder with and without comorbid PTSD and…
Somaia Mohamed, Gary R. Johnson, Varadan Sevilimedu, et al
JCP
Meta-Analysis

June 23, 2020

Women seem more likely than men to develop obsessive-compulsive disorder (OCD), but findings of individual studies are inconsistent. This meta-analysis estimated the worldwide prevalence of OCD to determine if…
Emily J. Fawcett, Hilary Power, Jonathan M. Fawcett
JCP
Brief Report

June 23, 2020

While many women wish to avoid antidepressants during pregnancy, such avoidance may lead to relapse. This small study evaluated the efficacy of gradual antidepressant discontinuation plus Preventive Cognitive Therapy…
Nina M. Molenaar, Marlies E. Brouwer, Huibert Burger, et al
JCP
Case Report

June 16, 2020

A 39-year-old man with schizophrenia develops paranoia about his neighbors and COVID-19 and then injures himself by applying cleaning products to his body. Read this case to see how…
Jessenia Morillo-González, Daniel Hernández-Huerta, Adislen Guillama-Henríquez, et al
JCP
Letter to the Editor

June 16, 2020

This letter comments on the article “Optimizing Treatment Choices to Improve Adherence and Outcomes in Schizophrenia” by Kane and Correll.
Hirofumi Hirakawa, Nobuyoshi Ishii
JCP
Letter to the Editor

June 16, 2020

Drs Kane and Correll reply to the letter “Depression as a Factor in Nonadherence in Schizophrenia” by Hirakawa and Ishii.
John M. Kane, Christoph U. Correll
JCP
Identifying Patients With Bipolar I Disorder Who Would Benefit From Maintenance Therapy With a Long-Acting Injectable Antipsychotic
Academic Highlights

June 16, 2020

In this article focusing on maintenance treatment of bipolar I disorder, experts discuss functional impairment, the potential for LAI antipsychotics to address nonadherence, and the characteristics of patients who…
Mauricio Tohen, Joseph F. Goldberg, Youssef Hassoun, et al
JCP
Original Research

June 16, 2020

Depressed people who have lost interest and are inactive may not respond well to antidepressants. This study examined whether depressed subjects with low interest and activity who responded poorly…
Rudolf Uher, Benicio N. Frey, Lena C. Quilty, et al

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