Letter to the Editor February 15, 2006

Panic Attacks Associated With Topiramate

Cristian Damsa, MD; Stella Warczyk, MD; Lionel Cailhol, MD; A. Melisande Kelley-Puskas, MD; Andrei Cicotti, MD; Coralie Lazignac, MD; Antonio Andreoli, MD

J Clin Psychiatry 2006;67(2):326-327

Article Abstract

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Sir: Although topiramate is not registered in Switzerland for the treatment of bipolar disorder, it is widely prescribed for this disorder, especially in patients suffering from comorbid conditions such as weight gain.1 We report a patient who experienced panic attacks associated with topiramate treatment. Case report. Ms. A, a 27-year-old woman with bipolar II disorder (according to the Structured Clinical Interview for DSM-IV Axis I Disorders2), had, in 2004, been stabilized for 3 months with lithium, 1200 mg/day.’ ‹