Prolonged QT Associated With an Overdose of Trazodone

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: QT prolongation, torsades de pointes ventricular tachycardia, and sudden death have been associated with a variety of neuropsychiatric medications, particularly neuroleptics and tricyclic antidepressants.¹ Case reports have documented QT prolongation after overdose with serotonin reuptake inhibitors.² Trazodone is an atypical antidepressant that has rarely been associated with QT prolongation in humans,^3-5 although an association has been reported in animals.⁶‘ ‹