Psychopharmacology: The Fourth Generation of Progress is the most comprehensive and up-to-date text on neuropsychopharmacology available. While I must admit I have not read it cover-to-cover (that monumental task would take several back-to-back sabbaticals) what I have read is thorough, complete, and lucid. The authors, largely but not entirely drawn from the American College of Neuropsychopharmacology, generally represent the most authoritative scholars in the world in each given area.
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