Quality of Life Among Patients With Depression

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Sir: Trivedi et al. are to be congratulated for their recent article describing the relationships between sociodemographic variables and various domains of health-related quality of life (HRQOL) in a large sample of depressed patients.¹ One of the primary findings of this article is that sociodemographic variables do not have a uniform effect on every HRQOL domain. The authors state that this report "uniquely demonstrates the importance of measurement of multiple domains of HRQOL"^1(p193); however, our research group² and others³ have emphasized the importance of measuring multiple domains in depression in earlier articles.