Educational Activity March 18, 2008

Relapse Prevention in Patients With Schizophrenia

John M. Kane, MD

J Clin Psychiatry 2008;69(4):e11

Article Abstract

Remission is a realistic goal for patients with schizophrenia, and, if sustained remission can be achieved, then patients may eventually attain functional recovery. The chance of relapse is decreased if patients are adherent to their pharmacotherapeutic treatment regimen. This case explores how to prevent relapse for a patient with schizophrenia and comorbid substance use disorder who is nonadherent to an oral atypical antipsychotic. To help the patient achieve treatment goals, intervention strategies such as switching medications and implementing psychosocial therapies are considered.

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