Letter to the Editor January 15, 2007

Reply to "Galantamine and QTc Prolongation"

Matthew W. Nelson, PharmD, BCPP; Robert W. Buchanan, MD

J Clin Psychiatry 2007;68(1):169-170

Article Abstract

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Sir: We appreciate and read with interest the comments by Drs. Brashear and Spivey. In response to our case report,1 they presented unpublished data from 2 studies performed by Johnson & Johnson Pharmaceutical Research and Development: 1 in subjects with schizophrenia and 1 in subjects with Alzheimer’s disease. Because these studies are unpublished, we are unable to evaluate important study sample details, such as subject age and gender, comorbid diseases, and concomitant medications, and therefore cannot comment on the relevance of their results to the case that we presented.