Letter to the Editor April 15, 1997

Reply to Letter to the Editor "Pharmacologic Properties of Venlafaxine"

Robert L. Findling; Michael A. Schwartz; Daniel J. Flannery; Michael J. Manos

J Clin Psychiatry 1997;58(4):178-179

Article Abstract

Letter to the Editor

Sir: We appreciate the interest Dr. Smith has taken in our work which examined venlafaxine in adults with attention- deficit/hyperactivity disorder (ADHD). However, our rationale for initiating a clinical trial with venlafaxine in adults with this syndrome was not simply due to the fact that venlafaxine is an antidepressant. The reason we initiated a trial with venlafaxine was that the effect of venlafaxine on both serotonergic and noradrenergic neural transmission is a pharmacologic profile shared with the tricyclic antidepressants.