Reply to Letter to the Editor "Relative Weight Gain Among Antipsychotics"

Letter to the Editor

Sir: I am very pleased that Dr. Masand has become one of the champions in psychiatry for promoting better recognition and treatment of the weight gain and obesity that psychotropic drugs can cause. I also agree with him that some atypical antipsychotics cause more average weight gain than others in clinical trials and have in fact written about this in a recent scholarly review and in my recent textbook. Table 1 is adapted from these publications and is a rank-order meta-analysis of those few studies that have reported on this important problem in psychiatry.