Schizophrenia Symptoms Remain Stable During Decreases From 2 Antipsychotics to Aripiprazole

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Sir: Like many others, we have become concerned about the increasing use of more than 1 antipsychotic medication for the maintenance treatment of schizophrenic illness. In an effort to determine whether more than 1 medication was superior to 1 alone, we performed the following small pilot study.

Method. The study was approved by the Massachusetts Mental Health Center Institutional Review Board and was conducted from August 2003 to June 2005.’ ‹