ASCP Corner October 31, 2008

The Search for Knowledge: Developing the American Psychiatric Association's Practice Guideline for Major Depressive Disorder

Alan J. Gelenberg, MD

J Clin Psychiatry 2008;69(10):1658-1659

Article Abstract

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Working in Boston in the late 1980s, I received a telephonecall from Byram Karasu, M.D. Byram was to chair the workgroupwriting the American Psychiatric Association’s (APA)first Practice Guideline for the Treatment of Patients WithMajor Depressive Disorder (MDD) and honored me with aninvitation to join. The first MDD Guideline was publishedin 1993. Byram chaired the workgroup that prepared the secondedition, which was published in 2000.’ ‹