ABSTRACT
Objective: In this study, we combined ecological momentary assessment (EMA) with traditional clinical follow-up to explore correlates of suicidal relapse in patients with a history of suicidal behavior.
Methods: Over 6 months, we followed up with 393 patients who completed baseline and follow-up interviews and were monitored through smartphone-based EMA via the MEmind app. Recruitment was conducted between February 2018 and March 2020. We recorded the occurrence of clinical suicidal events and EMA suicidal events, the latter defined as extreme scores on questions on passive suicide ideation.
Results: Fifteen percent of participants had a new clinical suicidal event during follow-up (9.2% suicide attempt [SA]; 5.9% emergency referral for suicidal ideation [SI]). Of the 319 participants who installed the MEmind app, 20.7% presented with EMA suicidal events. EMA suicidal events were statistically significantly associated with clinical suicidal events at 2-month follow-up but not at 6-month follow-up. In the Cox multivariate regression model, 5 factors were independently associated with clinical suicidal events: number of previous SAs, SA in the past year, SA in the past month (risk factors), female gender, and age (protective factors).
Conclusions: Our study confirms some of the risk factors classically associated with risk of suicide reattempt, such as history of suicidal behavior, while questioning others, such as female gender. Risk factors associated with EMA events differed from risk factors associated with traditional clinical suicide events, supporting the existence of distinct suicidal phenotypes.
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References (51)
- WHO. Mental Health. Prevention of Suicidal Behaviours: A Task for All. WHO website. https://www.who.int/news-room/fact-sheets/detail/suicide. Accessed January 10, 2021.
- Porras-Segovia A, Baca-García E, Courtet P, et al. If suicide were COVID-19: a neglected cause of premature death. J Clin Psychiatry. 2021;82(2):20l13702. PubMed CrossRef
- Franklin JC, Ribeiro JD, Fox KR, et al. Risk factors for suicidal thoughts and behaviors: a meta-analysis of 50 years of research. Psychol Bull. 2017;143(2):187–232. PubMed CrossRef
- Liu RT, Bettis AH, Burke TA. Characterizing the phenomenology of passive suicidal ideation: a systematic review and meta-analysis of its prevalence, psychiatric comorbidity, correlates, and comparisons with active suicidal ideation. Psychol Med. 2020;50(3):367–383. PubMed CrossRef
- Ghanbari B, Malakouti SK, Nojomi M, et al. Suicide prevention and follow-up services: a narrative review. Glob J Health Sci. 2015;8(5):145–153. PubMed CrossRef
- Gibb SJ, Beautrais AL, Fergusson DM. Mortality and further suicidal behaviour after an index suicide attempt: a 10-year study. Aust N Z J Psychiatry. 2005;39(1-2):95–100. PubMed CrossRef
- Parra-Uribe I, Blasco-Fontecilla H, Garcia-Parés G, et al. Risk of re-attempts and suicide death after a suicide attempt: a survival analysis. BMC Psychiatry. 2017;17(1):163. PubMed CrossRef
- Irigoyen M, Porras-Segovia A, Galván L, et al. Predictors of re-attempt in a cohort of suicide attempters: a survival analysis. J Affect Disord. 2019;247:20–28. PubMed CrossRef
- Grendas LN, Rojas SM, Puppo S, et al. Interaction between prospective risk factors in the prediction of suicide risk. J Affect Disord. 2019;258:144–150. PubMed CrossRef
- Aguglia A, Solano P, Parisi VM, et al. Predictors of relapse in high lethality suicide attempters: a six-month prospective study. J Affect Disord. 2020;271:328–335. PubMed CrossRef
- Kapur N, Cooper J, King-Hele S, et al. The repetition of suicidal behavior: a multicenter cohort study. J Clin Psychiatry. 2006;67(10):1599–1609. PubMed CrossRef
- Hayashi N, Igarashi M, Imai A, et al. Post-hospitalization course and predictive signs of suicidal behavior of suicidal patients admitted to a psychiatric hospital: a 2-year prospective follow-up study. BMC Psychiatry. 2012;12(1):186. PubMed CrossRef
- Courtet P, Picot MC, Bellivier F, et al. Serotonin transporter gene may be involved in short-term risk of subsequent suicide attempts. Biol Psychiatry. 2004;55(1):46–51. PubMed CrossRef
- Andover MS, Gibb BE, Miller IW. Time to emergence of severe suicidal ideation among psychiatric patients as a function of suicide attempt history. Compr Psychiatry. 2008;49(1):6–12. PubMed CrossRef
- Scoliers G, Portzky G, van Heeringen K, et al. Sociodemographic and psychopathological risk factors for repetition of attempted suicide: a 5-year follow-up study. Arch Suicide Res. 2009;13(3):201–213. PubMed CrossRef
- Nock MK, Borges G, Bromet EJ, et al. Suicide and suicidal behavior. Epidemiol Rev. 2008;30(1):133–154. PubMed CrossRef
- Goldney RD, Fisher LJ, Wilson DH, et al. Suicidal ideation and health-related quality of life in the community. Med J Aust. 2001;175(10):546–549. PubMed CrossRef
- Czyz EK, Berona J, King CA. Rehospitalization of suicidal adolescents in relation to course of suicidal ideation and future suicide attempts. Psychiatr Serv. 2016;67(3):332–338. PubMed CrossRef
- Posner K, Brown GK, Stanley B, et al. The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults. Am J Psychiatry. 2011;168(12):1266–1277. PubMed CrossRef
- Courtet P, Jollant F, Castelnau D, et al. Suicidal behavior: relationship between phenotype and serotonergic genotype. Am J Med Genet C Semin Med Genet. 2005;133C(1):25–33. PubMed CrossRef
- Turecki G. Dissecting the suicide phenotype: the role of impulsive-aggressive behaviours. J Psychiatry Neurosci. 2005;30(6):398–408. PubMed
- Bernanke JA, Stanley BH, Oquendo MA. Toward fine-grained phenotyping of suicidal behavior: the role of suicidal subtypes. Mol Psychiatry. 2017;22(8):1080–1081. PubMed CrossRef
- Oquendo MA, Bernanke JA. Suicide risk assessment: tools and challenges. World Psychiatry. 2017;16(1):28–29. PubMed CrossRef
- Sedano-Capdevila A, Porras-Segovia A, Bello HJ, et al. Use of ecological momentary assessment to study suicidal thoughts and behavior: a systematic review. Curr Psychiatry Rep. 2021;23(7):41. PubMed CrossRef
- Shiffman S, Stone AA, Hufford MR. Ecological momentary assessment. Annu Rev Clin Psychol. 2008;4(1):1–32. PubMed CrossRef
- Gee BL, Han J, Benassi H, et al. Suicidal thoughts, suicidal behaviours and self-harm in daily life: a systematic review of ecological momentary assessment studies. Digit Health. 2020;6:2055207620963958. PubMed CrossRef
- World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191–2194. PubMed CrossRef
- Berrouiguet S, Barrigón ML, Brandt SA, et al. Ecological assessment of clinicians’ antipsychotic prescription habits in psychiatric inpatients: a novel web- and mobile phone-based prototype for a dynamic clinical decision support system. J Med Internet Res. 2017;19(1):e25. PubMed CrossRef
- Barrigón ML, Berrouiguet S, Carballo JJ, et al; MEmind study group. User profiles of an electronic mental health tool for ecological momentary assessment: MEmind. Int J Methods Psychiatr Res. 2017;26(1):e1554. PubMed CrossRef
- Fartacek C, Schiepek G, Kunrath S, et al. Real-time monitoring of non-linear suicidal dynamics: methodology and a demonstrative case report. Front Psychol. 2016;7:130. PubMed CrossRef
- Bastien CH, Vallières A, Morin CM. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med. 2001;2(4):297–307. PubMed CrossRef
- Wilson MM, Thomas DR, Rubenstein LZ, et al. Appetite assessment: simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents. Am J Clin Nutr. 2005;82(5):1074–1081. PubMed CrossRef
- Al-Halabí S, Sáiz PA, Burón P, et al. Validation of a Spanish version of the Columbia-Suicide Severity Rating Scale (C-SSRS). Rev Psiquiatr Salud Ment. 2016;9(3):134–142. PubMed CrossRef
- Trivedi MH, Rush AJ, Ibrahim HM, et al. The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation. Psychol Med. 2004;34(1):73–82. PubMed CrossRef
- Federici S, Bracalenti M, Meloni F, et al. World Health Organization Disability Assessment Schedule 2.0: an international systematic review. Disabil Rehabil. 2017;39(23):2347–2380. PubMed CrossRef
- World Health Organization. International Statistical Classification of Diseases and Related Health Problems. 10th Revision. World Health Organization; 1994.
- Posner K, Oquendo MA, Gould M, et al. Columbia Classification Algorithm of Suicide Assessment (C-CASA): classification of suicidal events in the FDA’s pediatric suicidal risk analysis of antidepressants. Am J Psychiatry. 2007;164(7):1035–1043. PubMed CrossRef
- Chang SM, Matchar DB, Smetana GW, et al, eds. Appendix: Test Performance Metrics. In: Methods Guide for Medical Test Reviews. Rockville, Maryland: Agency for Healthcare Research and Quality (US); NIH website. June 2012. https://www.ncbi.nlm.nih.gov/books/NBK98249/. Accessed January 10, 2021.
- Gutiérrez-Rojas L, Porras-Segovia A, Dunne H, et al. Prevalence and correlates of major depressive disorder: a systematic review. Br J Psychiatry. 2020;42(6):657–672. PubMed CrossRef
- Ducasse D, Lopez-Castroman J, Dassa D, et al. Exploring the boundaries between borderline personality disorder and suicidal behavior disorder. Eur Arch Psychiatry Clin Neurosci. 2020;270(8):959–967. PubMed CrossRef
- Corcoran P, Keeley HS, O’Sullivan M, et al. The incidence and repetition of attempted suicide in Ireland. Eur J Public Health. 2004;14(1):19–23. PubMed CrossRef
- Wang SB, Coppersmith DDL, Kleiman EM, et al. A pilot study using frequent inpatient assessments of suicidal thinking to predict short-term postdischarge suicidal behavior. JAMA Netw Open. 2021;4(3):e210591. PubMed CrossRef
- Baumel A, Muench F, Edan S, et al. Objective user engagement with mental health apps: systematic search and panel-based usage analysis. J Med Internet Res. 2019;21(9):e14567. PubMed CrossRef
- Chung DT, Ryan CJ, Hadzi-Pavlovic D, et al. Suicide rates after discharge from psychiatric facilities: a systematic review and meta-analysis. JAMA Psychiatry. 2017;74(7):694–702. PubMed CrossRef
- Jiménez-Muñoz L, Peñuelas-Calvo I, Díaz-Oliván I, et al. Suicide prevention in your pocket: a systematic review of ecological momentary interventions for the management of suicidal thoughts and behaviors. Harv Rev Psychiatry. 2022;30(2):85–99.
- Hadzic A, Spangenberg L, Hallensleben N, et al. The association of trait impulsivity and suicidal ideation and its fluctuation in the context of the interpersonal theory of suicide. Compr Psychiatry. 2019;98:152158. PubMed CrossRef
- Oquendo MA, Porras-Segovia A. Barriers for the research, prevention, and treatment of suicidal behavior. Curr Top Behav Neurosci. 2020;46:25–40. PubMed CrossRef
- Ben-Zeev D, Scherer EA, Brian RM, et al. Use of multimodal technology to identify digital correlates of violence among inpatients with serious mental illness: a pilot study. Psychiatr Serv. 2017;68(10):1088–1092. PubMed CrossRef
- Porras-Segovia A, Molina-Madueño RM, Berrouiguet S, et al. Smartphone-based ecological momentary assessment (EMA) in psychiatric patients and student controls: a real-world feasibility study. J Affect Disord. 2020;274:733–741. PubMed CrossRef
- Lopez-Morinigo JD, Barrigón ML, Porras-Segovia A, et al. Use of ecological momentary assessment through a passive smartphone-based app (eB2) by patients with schizophrenia: acceptability study. J Med Internet Res. 2021;23(7):e26548. PubMed CrossRef
- Porras-Segovia A, Díaz-Oliván I, Barrigón ML, et al. Real-world feasibility and acceptability of real-time suicide risk monitoring via smartphones: A 6-month follow-up cohort. J Psychiatr Res. 2022;149:145–154. PubMed CrossRef
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