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Abstract

Although bipolar disorder cannot be cured, effective medications are available that can shorten the duration of illness episodes and reduce the rates of relapse. Unfortunately, treatment nonadherence is common among patients with bipolar disorder. Factors contributing to nonadherence vary, and nonadherence can be deliberate or accidental. Strategies to improve medication adherence include forming a strong alliance with patients, educating patients and their caregivers about the disorder and the importance of adherence, simplifying medication regimens, monitoring tolerability and proactively addressing adverse effects, and treating comorbid illnesses.