Article May 1, 2003

Treatment of Bipolar Disorder

Hans-Jürgen Möller, MD; Henry A. Nasrallah, MD

J Clin Psychiatry 2003;64(suppl 6):9-17

Article Abstract

Management strategies for bipolar disorder often entail relatively long-term, complex medicationregimens that combine primary mood stabilizers, antipsychotic agents, antidepressants, and othermedications, such as benzodiazepines. New strategies for the management of bipolar disorder haverecently been evaluated in controlled clinical trials, including using newer anticonvulsants, replacingconventional antipsychotics with atypical antipsychotics, and using novel combination treatments.This article provides an overview of current management strategies for patients with bipolar disorderand describes how these approaches can be incorporated into clinical practice.