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The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

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Letter to the Editor March 1, 2001

Treatment of Refractory Major Depression With Tramadol Monotherapy

Nathan Andrew Shapira; Marcia L. Verduin; John D. DeGraw

J Clin Psychiatry 2001;62(3):205-206

Article Abstract

Letter to the Editor

Sir: Recent reports describe treatment of patients with refractory major depression using augmentation with the µ-opiate agonists oxycodone and oxymorphone and the partial agonist buprenorphine. We report a patient with refractory major depression who responded to tramadol hydrochloride monotherapy.

 

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