Mood Disorders

Mood disorders, encompassing conditions like bipolar disorder and major depressive disorder, are complex and multifaceted. The Journal of Clinical Psychiatry offers comprehensive insights, from understanding their etiology to evidence-based therapeutic strategies. Our expert editors ensure content is clinically relevant, providing psychiatrists with the tools they need to offer effective and compassionate care to those grappling with mood disturbances.

Recently published articles about Mood Disorders

The Weekly Mind Reader: Fast New Mood Screener
news

April 28, 2023

The new Rapid Mood Screener can quickly and easily assess whether or not a patient's depression is associated with bipolar disorder.
JCP
Transdiagnostic PRS Prediction of Mood Disorders
Original Research

April 20, 2022

Mood disorders often co-occur with behavior disorders in children and adolescents. This study explored if polygenic risk scores based on external genome-wide association studies of these disorders could improve...
Eric J. Barnett, Joseph Biederman, Alysa E. Doyle, et al
JCP
Brief Report

August 17, 2021

This study examined childhood trauma and current traumatic stress ratings in bipolar and unipolar inpatients to see if higher levels of childhood trauma and current trauma symptoms are associated...
Amir Garakani, Frank D. Buono, Kaitlyn Larkin, et al
PCC
Letter to the Editor

January 14, 2021

In this letter to the editor, Dr Naguy comments on a report previously published in the PCC.
Ahmed Naguy
PCC
Case Report

January 7, 2021

This case report describes a patient who developed pneumonia during the course of clozapine treatment that abated after temporary cessation of clozapine and subsequent reintroduction at a lower dose.
Betsy D. McCollum, Paige K. Juettner, Charles I. Shelton
PCC
Case Report

September 10, 2020

Read a case of the antidepressant, Vortioxetine, which induced mania, causing graphorrhea in a bipolar patient.
Ahmed Naguy

Recent JCP Articles on Mood Disorders

JCP
Original Research

October 24, 2017

Therapeutic drug monitoring during clozapine therapy can be inconvenient as well as uncomfortable for patients. This study tested a novel method of dried blood spot (finger prick) monitoring as...
Lisanne M. Geers, Dan Cohen, Laura M. Wehkamp, et al
JCP
Original Research

July 18, 2017

In 2015, the FDA removed WBC monitoring altogether and reduced the threshold for ANCs before interruption of clozapine treatment was required. The current study looks at almost 250 clozapine-treated...
Ryan S. Sultan, Mark Olfson, Christoph U. Correll, et al
JCP
Article

March 29, 2017

The increasing overlap of mood disorders and antipsychotic use in youth is a growing area of concern. This meta-analysis examined the current findings on the frequency of mood disorders...
Chiara Cervesi, Su Young Park, Britta Galling, et al

Recent PCC Articles on Mood Disorders

PCC
Article

August 9, 2018

Do you screen for sleep disorders in patients with psychiatric conditions? Symptom overlap can mean that sleep disorders such as obstructive sleep apnea are overlooked in patients with posttraumatic...
Bettina S. Fehr, William F. Katz, Erin A. Van Enkevort, et al
PCC
Letter to the Editor

January 18, 2018

Clozapine can cause falls due to orthostatic hypotension or sedation, particularly in geriatric patients. A less-recognized cause of falls in clozapine patients is myoclonus, which manifests as knee buckling...
Betsy McCollum, Jaqueline Barclay, Jose de Leon
PCC
Letter to the Editor

August 10, 2017

Clozapine use can produce another side effect in some patients: elevated CPK. But when nothing else works and the patient finally shows response, should you risk a rechallenge even...
Yuka Takahashi, Tomomi Ogihara, Daimei Sasayama, et al

Featured Mood Disorders Research

PCC
Letter to the Editor

August 3, 2017

Clinicians should be able to recognize and manage potential side effects of clozapine, including myocarditis. However, treatment guidelines do not currently recommend a monitoring protocol for clozapine-induced myocarditis. This...
David R. Goldsmith, Robert O. Cotes
PCC
Letter to the Editor

June 15, 2017

Clozapine is the only antipsychotic approved for treatment-resistant schizophrenia; however, its use is limited due to potentially life-threatening side effects. Here, read the first report of an association between...
Tiago A. Duarte, Filipe D. G. Godinho, André L. B. Ferreira, et al
JCP
Article

February 22, 2017

What's the best way to switch to clozapine in patients with treatment-resistant schizophrenia? Do you worry that efficacy and tolerability will be compromised? This pilot, double-blind RCT addresses your...
Hiroyoshi Takeuchi, Jimmy Lee, Gagan Fervaha, et al
PCC
Case Report

June 4, 2020

The COVID-19 pandemic is a significant psychological stressor, impacting every facet of life. Here, read the case of a 37-year-old woman who developed mania, which was precipitated by stress...
N. A. Uvais
JCP
Meta-Analysis

May 26, 2020

First-line treatments for OCD include selective serotonin reuptake inhibitors and cognitive-behavioral therapy. But what do you do when patients do not respond to these or second-line strategies? In this...
Filipe Peste Martinho, Gonçalo Silva Duarte, Frederico Simões do Couto
JCP
Original Research

June 18, 2019

Women who take mood stabilizers have a greater risk of placenta-mediated pregnancy complications. But are the mood stabilizers themselves responsible for this higher risk? This study explores that question.
Jacqueline M. Cohen, Krista F. Huybrechts, Elisabetta Patorno, et al
PCC
Case Report

May 2, 2019

Clozapine is essential for the management of treatment-refractory schizophrenia, but its use is often limited by side effects. Read this report of a man who developed dysarthria and delirium...
Anna Shvartsur, Brent M. Kious
PCC
Letter to the Editor

February 28, 2019

Does olanzapine induce fever in some patients? Read this case report to find out more.
Tiago F. Ferreira, Filipe D. G. Godinho, Sara D. Dehanov, et al
JCP
Original Research

January 8, 2019

When treating patients with schizophrenia, achieving stable, long-term remission is an important step toward the goal of functional recovery. This study evaluated the effect of cariprazine on several measures...
Christoph U. Correll, Steven G. Potkin, Yan Zhong, et al

Celebrating
85 Years

Read the Journal of Clinical Psychiatry

Subscribe to read
more articles

Subscribe