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Case Report March 17, 2022

Mania Associated With Rhodiola Rosea: An Adaptogen With Antidepressant Effects

Rahat Whig, DO; Raphael J. Leo, MA, MD

Prim Care Companion CNS Disord 2022;24(2):21cr02980

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  1. Panossian AG, Efferth T, Shikov AN, et al. Evolution of the adaptogenic concept from traditional use to medical systems: pharmacology of stress- and aging-related diseases. Med Res Rev. 2021;41(1):630–703. PubMed CrossRef
  2. Mao JJ, Xie SX, Zee J, et al. Rhodiola rosea versus sertraline for major depressive disorder: a randomized placebo-controlled trial. Phytomedicine. 2015;22(3):394–399. PubMed CrossRef
  3. Brown RP, Gerbag PL, Ramazanov Z. Rhodiola rosea: a phytomedicinal overview. HerbalGram. 2002;56:40–52.
  4. Kazi SE, Karia R, Leontieva L. Herbal supplements: can they cause hypomania? Cureus. 2021;13(2):e13476. PubMed
  5. Norelli LJ, Xu C. Manic psychosis associated with ginseng: a report of two cases and discussion of the literature. J Diet suppl. 2015;12(2):119–125. PubMed CrossRef