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Rounds in the General Hospital

PCC
Clozapine: Its Use and Monitoring
Rounds in the General Hospital

July 30, 2024

The authors provide the latest information on clozapine use, including when your patients should receive or avoid taking it, what laboratory tests are required before and during administration, and…
Desta S. Lissanu, Chirag M. Vyas, Carol S. Lim, et al
PCC
Pharmacologic Management of TBI
Rounds in the General Hospital

July 16, 2024

Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on…
Sofia E. Matta, Christina LaCroix, Kaloyan Tanev, et al
PCC
Evaluation and Management of Treatment-Resistant Schizophrenia
Rounds in the General Hospital

July 2, 2024

If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette…
Carol S. Lim, Abigail L. Donovan, Chirag M. Vyas, et al
PCC
Neuropsychiatric Complications of Hypervitaminosis D
Rounds in the General Hospital

June 13, 2024

A 28-year-old man presented to the emergency department with severe agitation, insomnia, weakness, constipation, and muscle jerks after nonsuicidal overdosing of vitamin D.
James K. Rustad, Adam Z. Spitz, Brandon C. Wilson, et al
PCC
Impact of Disability on Medical Care
Rounds in the General Hospital

June 6, 2024

Given that many people have disabilities, physicians should develop skills that assess the level of disability, the functional consequence of illness, and the social and physical environments of patients…
Mirza Baig, Andrew S. Chun, Ashika Bains, et al
PCC
Management of Rumination and Obsessions in Primary Care
Rounds in the General Hospital

May 30, 2024

Difficult-to-control negative repetitive thoughts can manifest as ruminations or obsessions. Appropriate early identification and intervention can positively affect the course and prevent an episode of psychiatric illness.
Sharmin Ghaznavi, Charlotte Schiewe, Theodore A. Stern

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More PCC Articles

JCP
Maternal Postnatal Depression and Infant Immunizations
Original Research

June 13, 2022

The relationship between maternal postnatal depression and infant vaccination is uncertain. This study examined whether infants of mothers who sought support for postnatal depression were less likely to receive…
Holly C. Smith, Sonia Saxena, Irene Petersen
JCP
Predictors of Suicidality After Psychiatric Hospitalization
Original Research

June 13, 2022

This study examined the incidence and predictors of suicide attempts and deaths in the year after psychiatric hospitalization; covariates included sex, geographic location, and physical health conditions.
Jessica S. Enns, Natalie P. Mota, James M. Bolton, et al
JCP
Accumulation of Reproductive Safety Data for SGAs
Commentary

June 8, 2022

This commentary on an article by Yakuwa and colleagues calls for an acceleration of the acquisition of clinical data on the safety of second-generation antipsychotics for pregnant women and…
Adele C. Viguera
JCP
Pregnancy Outcomes With First-Trimester SGA Exposure
Original Research

June 8, 2022

In Japan, information regarding the effects of antipsychotics on the fetus during pregnancy is limited. This Japanese study examined the association between the use of antipsychotics during pregnancy and…
Naho Yakuwa, Kunihiko Takahashi, Tatsuhiko Anzai, et al
JCP
Psychiatric Patients Who Do Not Believe They Deserve to Get Better
Brief Report

June 8, 2022

This study of 405 patients in a partial hospital program examined the prevalence of the belief of “undeservingness” (ie, that one does not deserve to be treated) and the…
Mark Zimmerman, Lena Becker
JCP
Transdermal HP-3070 for Hostility in Schizophrenia
Original Research

June 6, 2022

Schizophrenia is sometimes accompanied by aggressive, hostile behavior, particularly during the acute phase. This post hoc analysis of a phase 3 study examines the efficacy of transdermal asenapine (HP-3070)…
Leslie Citrome, Marina Komaroff, Brittney Starling, et al
JCP
Suicide Risk in a National VA Sample
Original Research

June 6, 2022

Predicting suicide is difficult, as suicidal behavior is not linked solely to any single behavior or psychiatric diagnosis. This study compared risk of suicidal behavior among a transdiagnostic sample…
Alan C. Swann, David P. Graham, Anna V. Wilkinson, et al
JCP
Long-term Outcomes of Early Use of LAIs in Schizophrenia
Original Research

June 1, 2022

Using data from the Taiwan National Health Insurance Research Database, the authors compared long-term effectiveness of switching to long-acting injectable antipsychotics versus remaining on oral antipsychotics.
Su-Chen Fang, Cheng-Yi Huang, Yu-Hsuan Joni Shao
JCP
Efficacy and Safety of AXS-05 (Dextromethorphan-Bupropion) in MDD
Original Research

May 30, 2022

Altered glutamatergic neurotransmission has been implicated in the pathogenesis of depression. This phase 3 trial evaluated the efficacy and safety of AXS-05 (dextromethorphan-bupropion) in the treatment of major depressive…
Dan V. Iosifescu, Amanda Jones, Cedric O’Gorman, et al
JCP
ADHD, ASD, and Other Neurodevelopmental Outcomes Associated With Antipsychotic Exposure During Pregnancy
Clinical and Practical Psychopharmacology

May 30, 2022

Dr Andrade discusses the implications of 2 recent large cohort studies examining risk of neurodevelopmental disorders after gestational exposure to antidepressants.
Chittaranjan Andrade
JCP
Antidepressant Drugs and Health-Related QoL: A Guide to Examining a “Viral” Research Paper
Clinical and Practical Psychopharmacology

May 25, 2022

A recent study reporting no improvement in health-related quality of life with antidepressants went “viral” in the mass media. Here, Dr Andrade considers the shortcomings of the study and…
Chittaranjan Andrade
JCP
Should Blind Psychiatrists Be Paid Less?
Commentary

May 23, 2022

Dr Zimmerman comments on a recent meta-analysis by Scott and colleagues on the use of video-based telehealth in treatment of PTSD.
Mark Zimmerman, MD

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