Advancing primary care with essential peer-reviewed research and insights into CNS disorders
Rounds in the General Hospital
Rounds in the General Hospital
Management of Rumination and Obsessions in Primary Care
May 30, 2024
Difficult-to-control negative repetitive thoughts can manifest as ruminations or obsessions. Appropriate early identification and intervention can positively affect the course and prevent an episode of psychiatric illness.
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More PCC Articles
Original Research
Differences Among Second-Generation Antipsychotics in Effects on HbA1c
March 30, 2022
The antipsychotic blonanserin was associated with less change in glycated hemoglobin (HbA1c) levels than olanzapine, and changes in BMI were lower for both blonanserin and aripiprazole. Study results indicate…
Clinical and Practical Psychopharmacology
Insights on Use of Ketamine From RCTs of Ketamine vs Electroconvulsive Therapy in Severe Depression
March 28, 2022
ECT outperformed ketamine in recent randomized controlled trials. These studies also, however, shed light on ketamine’s potential as a viable alternative to ECT in some severely depressed patients.
Original Research
Quetiapine XR in Comorbid Depression and Anxiety
March 21, 2022
Quetiapine is often used off-label for anxiety and as an augmentation agent in treatment-resistant depression. This study evaluated the efficacy and tolerability of quetiapine in augmenting first-line antidepressants for…
Original Research
Deimplementation of Benzodiazepine Prescribing for PTSD Among Veterans
March 14, 2022
Given concerns about inappropriate prescribing in post-9/11 veterans, a goal of the Veterans Health Administration has been to reduce off-label prescribing practices. This study tracks benzodiazepine prescribing for PTSD…
Original Research
HSA-HDHPs and Bipolar Disorder Medication Cost Burden
March 9, 2022
This study examined the effects of high-deductible health plans paired with health savings accounts (HSA-HDHPs)—which require substantial out-of-pocket spending for most services—on medication out-of-pocket spending in people with bipolar…
ASCP Corner
Cardiovascular Health in Severe Mental Illness: Potential Role for Metformin
March 9, 2022
Patients with severe mental illnesses often also have metabolic disorders such as obesity and diabetes. This article discusses a preventive approach to the problem: incorporating early pharmacologic intervention to…
