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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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Rounds in the General Hospital

PCC
Clozapine: Its Use and Monitoring
Rounds in the General Hospital

July 30, 2024

The authors provide the latest information on clozapine use, including when your patients should receive or avoid taking it, what laboratory tests are required before and during administration, and…
Desta S. Lissanu, Chirag M. Vyas, Carol S. Lim, et al
PCC
Pharmacologic Management of TBI
Rounds in the General Hospital

July 16, 2024

Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on…
Sofia E. Matta, Christina LaCroix, Kaloyan Tanev, et al
PCC
Evaluation and Management of Treatment-Resistant Schizophrenia
Rounds in the General Hospital

July 2, 2024

If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette…
Carol S. Lim, Abigail L. Donovan, Chirag M. Vyas, et al
PCC
Neuropsychiatric Complications of Hypervitaminosis D
Rounds in the General Hospital

June 13, 2024

A 28-year-old man presented to the emergency department with severe agitation, insomnia, weakness, constipation, and muscle jerks after nonsuicidal overdosing of vitamin D.
James K. Rustad, Adam Z. Spitz, Brandon C. Wilson, et al
PCC
Impact of Disability on Medical Care
Rounds in the General Hospital

June 6, 2024

Given that many people have disabilities, physicians should develop skills that assess the level of disability, the functional consequence of illness, and the social and physical environments of patients…
Mirza Baig, Andrew S. Chun, Ashika Bains, et al
PCC
Management of Rumination and Obsessions in Primary Care
Rounds in the General Hospital

May 30, 2024

Difficult-to-control negative repetitive thoughts can manifest as ruminations or obsessions. Appropriate early identification and intervention can positively affect the course and prevent an episode of psychiatric illness.
Sharmin Ghaznavi, Charlotte Schiewe, Theodore A. Stern

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More PCC Articles

JCP
Original Research

July 3, 2018

Read a randomized control trial evaluating tianeptine’s efficacy in patients 65 and older with recurrent major depressive disorder (MDD).
Robin Emsley, Antti Ahokas, Aldo Suarez, et al
JCP
Original Research

June 26, 2018

Reports on the efficacy of omega-3 fatty acids for depression are mixed, with only limited data in adolescents.  This RCT compared their efficacy versus placebo in 51 adolescents with…
Vilma Gabbay, Rachel D. Freed, Carmen M. Alonso, et al
JCP
Original Research

June 26, 2018

Clinical Practice Guidelines have been published by the US military to aid in clinical management of patients with PTSD. To investigate whether these best-practice guidelines are being followed, this…
George Loeffler, Rachael Coller, LaRee Tracy, et al
JCP
ASCP Corner

June 26, 2018

Cannabis use is increasingly visible as policy shifts toward legalization in many states. What should clinicians know about treating patients who use cannabis? This ASCP Corner article examines the…
Derek D. Satre, Amber Bahorik, Tauheed Zaman, et al
JCP
Educational Activity

June 26, 2018

Although levodopa is effective for treating Parkinson disease, physicians and patients face significant management challenges related to disease progression. Patients may develop fluctuations in motor symptoms and dyskinesias as…
Adolfo Ramirez-Zamora
JCP
Original Research

June 19, 2018

Augmentation of antidepressants with aripiprazole is effective in treating late-life depression. As an antipsychotic medication, however, aripiprazole potentially leads to extrapyramidal side effects (EPS). Read this article to learn…
Jonathan H. Hsu, Benoit H. Mulsant, Eric J. Lenze, et al
JCP
Original Research

June 19, 2018

High rates of schizophrenia symptom recurrence after antipsychotic treatment discontinuation are are thought to be due to withdrawal-related phenomena rather than illness recurrence. This post hoc analysis examines results…
Robin Emsley, Isaac Nuamah, Srihari Gopal, et al
JCP
Article

June 12, 2018

How common is illicit drug use among current and former cigarette smokers? If marijuana isn’ t considered illicit, does that change the prevalence of illicit drug use? Can illicit…
Scott J. Moeller, David S. Fink, Misato Gbedemah, et al
JCP
Original Research

June 12, 2018

Individuals with depression can experience diminished levels of reward positivity (RewP), a neurophysiologic index of reward responsiveness. Can changing levels of RewP be used as an objective index of…
Katie L. Burkhouse, Stephanie M. Gorka, Heide Klumpp, et al
JCP
Review Article

June 5, 2018

Read a full article of a systematic review on 12 studies associating cannabis use with long-term anxiety or mood disorders.
George Mammen, Sergio Rueda, Michael Roerecke, et al
JCP
Meta-Analysis

June 5, 2018

Internet addiction has been associated with other psychiatric disorders and with higher rates of suicidality. This meta-analysis looks at the risk of suicidality, factors that could modify the risk…
Yu-Shian Cheng, Ping-Tao Tseng, Pao-Yen Lin, et al
JCP
Perspective

May 29, 2018

The recent FDA approval of aripiprazole tablets with sensor met with a myriad of reactions, including concerns about patient privacy and autonomy. In this Perspectives article, authors from the…
Daniel J. Lee, Tiffany R. Farchione, Mitchell V. Mathis, et al

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