Harold A. Sackeim, PhD

Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina

  • 12Articles
  • 52.8KReads
  • 1999–2026Active
  • 81Collaborators
  • 370Citations

About

Harold A. Sackeim, PhD is affiliated with Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina. Harold A. Sackeim has authored or co-authored 12 peer-reviewed articles published across the Journal of Clinical Psychiatry and the Primary Care Companion for CNS Disorders between 1999 and 2026. Their work focuses on Depression (MDD), Suicide, Electroconvulsive Therapy, and Psychedelics.

Publications

JCP
Impact of VNS on Suicidal Ideation in Markedly Treatment-Resistant Major Depression: A RECOVER Study Report
Original Research ▶ Video

Impact of VNS on Suicidal Ideation in Markedly Treatment-Resistant Major Depression: A RECOVER Study Report

July 8, 2026

Findings suggest that active VNS reduces suicidal ideation (SI) and potentially induces SI remission among participants with chronic TRD and baseline SI.
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JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
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JCP
Predictors of Treatment Response to Adjunctive VNS Therapy in Major Depressive Disorder: A RECOVER Trial Report
Original Research

Predictors of Treatment Response to Adjunctive VNS Therapy in Major Depressive Disorder: A RECOVER Trial Report

July 14, 2025

History of ECT use (lifetime and current episode) or TMS use (current episode) was prognostic of poorer outcomes across the total sample and superior benefit from active versus sham...
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JCP
TMS in Anxious Depression
Original Research

TMS in Anxious Depression

January 11, 2023

Patients with anxious depression tend to have more severe depressive symptoms. This study examined the effects of transcranial magnetic stimulation in these patients.
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JCP
Original Research

A Multisite, Naturalistic, Observational Study of Transcranial Magnetic Stimulation for Patients With Pharmacoresistant Major Depressive Disorder: Durability of Benefit Over a 1-Year Follow-Up Period

September 16, 2014

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JCP
Original Research

Factors Associated With Health-Related Quality of Life Among Outpatients With Major Depressive Disorder: A STAR*D Report.

February 15, 2006

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JCP
Original Research

Two-Year Outcome of Vagus Nerve Stimulation (VNS) for Treatment of Major Depressive Episodes

September 15, 2005

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JCP
Original Research

Predictors of Remission After Electroconvulsive Therapy in Unipolar Major Depression

August 15, 2005

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JCP
Original Research

A Computer Algorithm for Calculating the Adequacy of Antidepressant Treatment in Unipolar and Bipolar Depression

July 15, 2003

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JCP
Article

The Definition and Meaning of Treatment-Resistant Depression

January 2, 2001

JCP
Original Research

The Texas Medication Algorithm Project: Report of the Texas Consensus Conference Panel on Medication Treatment of Major Depressive Disorder

March 31, 1999

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JCP
Article

Electroconvulsive Therapy and Suicide Risk

February 1, 1999

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Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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