Publications
Original Research
▶ Video
Impact of VNS on Suicidal Ideation in Markedly Treatment-Resistant Major Depression: A RECOVER Study Report
July 8, 2026
Findings suggest that active VNS reduces suicidal ideation (SI) and potentially induces SI remission among participants with chronic TRD and baseline SI.
Original Research
Predictors of Treatment Response to Adjunctive VNS Therapy in Major Depressive Disorder: A RECOVER Trial Report
July 14, 2025
History of ECT use (lifetime and current episode) or TMS use (current episode) was prognostic of poorer outcomes across the total sample and superior benefit from active versus sham...
Consensus Statement
Developing a Treatment-Resistant Depression Consultation Program, Part II: Assessment
May 7, 2025
Consensus recommendations about the goals of a consultation for treatment-resistant depression include establishing the primary diagnosis and comorbidities, clarifying symptoms, identifying goals, documenting treatment history, identifying treatment barriers, and...
Consensus Statement
Developing a Treatment-Resistant Depression Consultation Program, Part I: Practical and Logistical Considerations
April 28, 2025
Key practical considerations are described, including systems-level and financial issues; equity and access to TRD care for a diverse population; selecting a target population and facilitating referrals; communication between...
Insights
Surgical Interventions in Treatment Resistant Depression
October 7, 2024
Patricio Riva Posse, MD, discusses advanced surgical interventions for treatment-resistant depression, including vagus nerve and deep brain stimulation. This presentation explores relapse rates, alternative therapies, and the potential for...
