The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Cardiac Malformation Risks After First Trimester Methylphenidate Use
Brief Report

May 15, 2023

This meta-analysis found that use of methylphenidate in the first trimester may be a risk factor for fetal congenital heart defects.
Jonathan L. Richardson, Nathan George, Amanda J. Greenall, et al
JCP
Research Participant Feedback on a Suicide Safety Protocol
Original Research

May 15, 2023

In women who triggered a safety protocol as part of a perinatal suicidal ideation study, 50% reported that the protocol increased engagement with treatment, and most reported a “positive…
Rachel Vanderkruik, Marlene P. Freeman, Katherine A. Dunn, et al
JCP
Control Conditions in Randomized Trials of Psychedelics: An ACTTION Systematic Review
Systematic Review

May 10, 2023

Randomized trials of psychedelics underutilize blind assessment, active drug controls, and testing psychological support against minimal-support conditions—elements that would improve quality or provide important information.
Sandeep M. Nayak, Melissa K. Bradley, Bethea A. Kleykamp, et al
JCP
Depression Treatment Response Beyond 50% Improvement
Original Research

May 8, 2023

Although most depression treatment research focuses on symptom improvement, patients have additional treatment priorities, including functioning, coping ability, and quality of life.
Mark Zimmerman, Sin-Ying Lin
JCP
Low Ghrelin and Anxiety in ARFID
Original Research

May 3, 2023

Low ghrelin levels were associated with greater anxiety in ARFID, indicating a potential target in the treatment of this disorder.
Aluma Chovel Sella, Natalia Hadaway, Casey Stern, et al
JCP
Endothelial Function in Youth With Bipolar Disorder
Original Research

May 1, 2023

Bipolar disorder (BD) confers risk for accelerated atherosclerosis and early cardiovascular disease. This study found that youth with BD have anomalous reactive hyperemia index (RHI)—a measure of endothelial function—which…
Kody G. Kennedy, Sudhir Karthikeyan, Alysha A. Sultan, et al
JCP
Abbreviated Suicide Crisis Syndrome Checklist and Decision Making in the ED
Original Research

May 1, 2023

The A-SCS-C had robust clinical utility and reduced clinicians’ reliance on patient-reported suicidal ideation to assess suicide risk in the ED setting.
Ethan Karsen, Lisa J. Cohen, Betsy White, et al
JCP
rTMS for Treatment-Resistant Depression: Mismatch of Evidence and Insurance Coverage Policies
Commentary

April 26, 2023

The authors argue that insurance companies’ prior authorization process overly restricts access to rTMS, which has proven effectiveness for TRD.
Cory R. Weissman, Richard A. Bermudes, Jeffrey Voigt, et al
JCP
Efficacy of Lumateperone in Bipolar Depression With Mixed Features
Original Research

April 24, 2023

Lumateperone significantly improved depression symptoms, disease severity, and quality of life in patients with bipolar depression with mixed features.
Roger S. McIntyre, Suresh Durgam, Jason Huo, et al
JCP
Pregnancy-Specific Anxiety Tool: Development and Psychometric Evaluation
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ April 19, 2023

The Pregnancy-Specific Anxiety Tool contributes new dimensions to the measurement of anxiety in pregnancy. Patients scoring higher than 10 on the PSAT require further assessment.
Hamideh Bayrampour, Richard E. Hohn, Sukhpreet K. Tamana, et al
JCP
LAI Implementation After Schizophrenia Diagnosis
Original Research

April 19, 2023

Although long-acting injectable antipsychotic agents (LAIs) are effective in preventing relapse, their use in first-episode schizophrenia was low, and LAIs were rarely the first therapy for early-phase schizophrenia.
John M. Kane, Marko A. Mychaskiw, Sangtaeck Lim, et al
JCP
Depression and Cue Reactivity in Opioid Use Disorder Patients Receiving Extended-Release Naltrexone
Brief Report

April 17, 2023

Greater depression severity was linked to less reduction in cue-induced craving during naltrexone treatment for OUD.
Zhenhao Shi, Xinyi Li, Kyle M. Kampman, et al

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