The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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More JCP Articles

JCP
The GABA Pathway and New Clinical Trial Data in MDD and PPD
Supplement Article

March 16, 2023

Studies evaluating neuroactive steroid GABA-A receptor positive allosteric modulators demonstrate promising results for the treatment of MDD and PPD.
Kristina M. Deligiannidis, Anita H. Clayton
JCP
Protective Effect of Clozapine on Suicide
Original Research

March 15, 2023

Clozapine, which has shown promise in reducing suicidal behavior in schizophrenia, also appears to lower the odds of suicide death in the general population.
Brian J. Lee, Robert O. Cotes, Ramin Mojtabai, et al
JCP
Neighborhood Vulnerability in First-Episode Psychosis
Original Research

March 13, 2023

Psychosocial difficulties in people with first-episode psychosis could be related to a lack of resources in the area where they live.
Ana Izquierdo, María Cabello, Itziar Leal, et al
JCP
Doxazosin for the Treatment of PTSD and AUD
Original Research

March 8, 2023

This study is the first to evaluate doxazosin, an α1-adrenergic antagonist, in veterans with both PTSD and alcohol use disorder.
Sudie E. Back, Julianne C. Flanagan, Jim Mintz, et al
JCP
When and How to Use Lithium Augmentation for MDD
ASCP Corner

March 8, 2023

With its antisuicidal effect and low cost, lithium can be an effective alternative to other MDD augmentation strategies when antidepressants are not enough.
Mete Ercis, Aysegul Ozerdem, Balwinder Singh
JCP
NNT, NNH, and LHH for Lumateperone
Original Research

March 6, 2023

The benefit-risk assessment of lumateperone was favorable as measured by number-needed-to-treat and number-needed-to-harm analyses.
Leslie Citrome, Suresh Durgam, John B. Edwards, et al
JCP
Preventive Health Care in Children and Maternal Schizophrenia
Original Research

March 1, 2023

About 50.3% of children born to mothers with schizophrenia had an enhanced 18-month well-baby visit versus 58.6% of those whose mothers did not have schizophrenia.
Clare L. Taylor, Hilary K. Brown, Natasha R. Saunders, et al
JCP
Suicide Attempts and Health-Related Quality of Life
Original Research

February 27, 2023

People with recent suicide attempts have much lower mental health–related QOL than those with no attempt or an attempt in the distant past. Psychiatric and substance use comorbidities explain…
Tanner J. Bommersbach, Robert A. Rosenheck, Taeho Greg Rhee
JCP
In Memoriam: Joseph Biederman, MD
In Memoriam

February 22, 2023

Colleagues and friends remember Joseph Biederman and reflect on his legacy as the father of pediatric psychopharmacology.
Timothy E. Wilens, Janet R. Wozniak, Lee S. Cohen, et al
JCP
Resilience in Bipolar Disorder
Systematic Review

February 22, 2023

Bipolar disorder patients with greater resilience had less severe symptoms, more positive attitudes toward medication treatment, and better social support and functioning.
Min Kai Chan, Qian Hui Chew, Kang Sim
JCP
PTSD in Survivors of the 1999 Izmit Earthquake: A 10-Year Follow-Up Study
Original Research

February 20, 2023

In survivors of the 1999 earthquake in Izmit, Turkey, PTSD symptoms decreased in the first 2 years, but remained stable after 10 years.
Oguz K. Karamustafalıoğlu, Leah Fostick, Mehmet Çevik, et al
JCP
Effect of Zuranolone vs Placebo in MDD
Original Research

February 20, 2023

This phase 3 RCT found significant improvement in depressive symptoms with zuranolone beginning at day 3 of treatment.
Anita H. Clayton, Robert Lasser, Indrani Nandy, et al

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