Letter to the Editor April 26, 2018

Prevention of Dopamine Dysregulation Syndrome in Parkinson's Disease: A Case Report

Walter T. Luchsinger, MD; Natasha Gambhir, BS; Dustin DeMoss, DO

Prim Care Companion CNS Disord 2018;20(2):17l02127

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To the Editor: Parkinson’s disease (PD) is a common neurodegenerative disease that affects 1 million people in the United States. The current recommended treatments for PD are carbidopa/levodopa and dopamine agonists. While carbidopa/levodopa is relatively safe for PD patients, dopamine agonists have been associated with many adverse effects such as hallucinations, compulsive behaviors, orthostatic hypotension, somnolence, peripheral edema, and nausea.

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