Enhance Your Understanding of Lithium Neurotoxicity

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To the Editor: Lithium is a drug established for treatment of affective disorder and is intended to mitigate and prevent depressive or manic episodes and diminish suicidal tendencies. However, lithium can induce neurologic sequelae following overdose or during maintenance therapy.

Neurotoxicity. Lithium neurotoxicity can be reversible or irreversible and may even be observed at therapeutic serum levels.