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Rounds in the General Hospital

PCC
Clozapine: Its Use and Monitoring
Rounds in the General Hospital

July 30, 2024

The authors provide the latest information on clozapine use, including when your patients should receive or avoid taking it, what laboratory tests are required before and during administration, and…
Desta S. Lissanu, Chirag M. Vyas, Carol S. Lim, et al
PCC
Pharmacologic Management of TBI
Rounds in the General Hospital

July 16, 2024

Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on…
Sofia E. Matta, Christina LaCroix, Kaloyan Tanev, et al
PCC
Evaluation and Management of Treatment-Resistant Schizophrenia
Rounds in the General Hospital

July 2, 2024

If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette…
Carol S. Lim, Abigail L. Donovan, Chirag M. Vyas, et al
PCC
Neuropsychiatric Complications of Hypervitaminosis D
Rounds in the General Hospital

June 13, 2024

A 28-year-old man presented to the emergency department with severe agitation, insomnia, weakness, constipation, and muscle jerks after nonsuicidal overdosing of vitamin D.
James K. Rustad, Adam Z. Spitz, Brandon C. Wilson, et al
PCC
Impact of Disability on Medical Care
Rounds in the General Hospital

June 6, 2024

Given that many people have disabilities, physicians should develop skills that assess the level of disability, the functional consequence of illness, and the social and physical environments of patients…
Mirza Baig, Andrew S. Chun, Ashika Bains, et al
PCC
Management of Rumination and Obsessions in Primary Care
Rounds in the General Hospital

May 30, 2024

Difficult-to-control negative repetitive thoughts can manifest as ruminations or obsessions. Appropriate early identification and intervention can positively affect the course and prevent an episode of psychiatric illness.
Sharmin Ghaznavi, Charlotte Schiewe, Theodore A. Stern

Page 12

More PCC Articles

JCP
Clozapine Delay and Schizophrenia Outcomes
Original Research

August 23, 2023

Clozapine is the drug of choice for treatment-resistant schizophrenia, but delays in initiation and underutilization may hinder its effectiveness. This study examined whether delay in clozapine initiation led to…
Claire Law, Yuen Mei See, Jie Yin Yee, et al
JCP
COVID-19 Delirium and Motoric Subtypes: Improving Outcomes
Commentary

August 21, 2023

Randall T. Espinoza, MD, and Aaron Kaufman, MD, discuss a study by Trevisan et al and reflect on lessons learned during the pandemic about detecting and managing delirium.
Randall T. Espinoza, Aaron Kaufman
JCP
Delirium and Mortality in COVID-19 Patients
Original Research

August 21, 2023

COVID-19 patients with early onset delirium had a 2-fold increased mortality risk—both in-hospital and after discharge—than those without delirium.
Caterina Trevisan, Giulia Grande, Paola Rebora, et al
JCP
Nitrous Oxide Reduced Suicidal Ideation in Treatment-Resistant Major Depression
Brief Report

August 16, 2023

In this exploratory analysis, 54% of TRD patients receiving nitrous oxide had a reduction in suicidal ideation, compared with 12% in the placebo group.
Victoria C. de Leon, Arun Kumar, Peter Nagele, et al
JCP
Adjunctive Cariprazine for MDD With Inadequate Response to Antidepressants
Original Research

August 16, 2023

This study assessed the efficacy of adjunctive use of cariprazine, an atypical antipsychotic, in MDD patients with inadequate response to antidepressants.
Robert Riesenberg, Paul P. Yeung, Ludmyla Rekeda, et al
JCP
Developments in Major Depressive Disorder Therapy
DELETE CME Institute Showcase

August 14, 2023

Among the greatest unmet needs in MDD is for effective pharmacotherapies for patients who do not respond to first- and second-line antidepressant medications. After decades of muted progress, alternatives…
Michael E. Thase
JCP
Evolving Research on Postpartum Depression Pathophysiology and Treatment
DELETE CME Institute Showcase

August 14, 2023

Research on neuroactive steroids reveals their role in perinatal depression, leading to development of novel therapeutics. These emerging treatments hold promise for faster onset and lasting effects.  
Kristina M. Deligiannidis, Rubiahna Vaughn
JCP
Emerging Therapies for Attention-Deficit/Hyperactivity Disorder
DELETE CME Institute Showcase

August 9, 2023

While patients with ADHD today still face numerous unmet needs, a number of newer pharmacologic agents and devices with potential advantages over traditional therapies have emerged and gained regulatory…
Jeffrey H. Newcorn
JCP
Fiscal Impact of Schizophrenia From a Government Perspective
Original Research

August 9, 2023

This analysis revealed that the lifetime fiscal loss to the government was $1,540,042 for each person with schizophrenia.
Rui Martins, Aditi Kadakia, G. Rhys Williams, et al
JCP
Emerging Perspectives in Addiction Psychiatry
DELETE CME Institute Showcase

August 9, 2023

FDA-approved medications and early intervention for people with substance use disorders should be encouraged as early as possible to optimize patient outcomes and life expectancy.
Ayana Jordan
JCP
Using Percentiles to Understand Standardized Mean Difference as a Measure of Effect Size
Clinical and Practical Psychopharmacology

August 7, 2023

Chittaranjan Andrade, MD, explains the use of SMDs as a measure of effect size. A recent meta-analysis of the effect of ChEIs on hallucinations and delusions in Alzheimer and…
Chittaranjan Andrade
JCP
Non-Dopaminergic Mechanisms for Schizophrenia Symptom Management
DELETE CME Institute Showcase

August 7, 2023

Next generation therapeutics that work well, are better tolerated, and lead to improved outcomes may offer a different treatment approach for patients with schizophrenia.
Leslie Citrome, Jonathan M. Meyer

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