Advancing primary care with essential peer-reviewed research and insights into CNS disorders
Rounds in the General Hospital
Rounds in the General Hospital
Management of Rumination and Obsessions in Primary Care
May 30, 2024
Difficult-to-control negative repetitive thoughts can manifest as ruminations or obsessions. Appropriate early identification and intervention can positively affect the course and prevent an episode of psychiatric illness.
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Commentary
Can Our Collective Experiences As Clinicians Improve Mental Health Care?
July 17, 2024
Drs Rush and Tramontin discuss how simple outcomes, often patient reported, could facilitate evidence-based decision making by clinicians, administrators, and payors and provide the foundation for a learning health…
Original Research
Underdiagnosis, Undertreatment, and Noncompliance With Treatment in People Who Died by Suicide
July 10, 2024
Depression was diagnosed prior to death in 18.6% of people with a major depressive episode who died by suicide. Antidepressants were prescribed in 21.5% of these individuals, but only…
Clinical and Practical Psychopharmacology
Epilepsy, Antiepileptic Drugs, and Adverse Pregnancy Outcomes, 2: Major Congenital Malformations
July 3, 2024
This article reviews evidence from a large registry, a population-based study, and a meta-analysis on the risks of major congenital malformation with untreated epilepsy and with exposure to antiepileptic…
Original Research
Borderline Personality Disorder and Eating Disorders: The Role of Emotion Regulation
July 3, 2024
Deficits in emotion regulation significantly predicted borderline personality disorder (BPD). Although eating disorders were not significantly predicted by emotion regulation deficits, they did predict BPD diagnoses.
Narrative Review
Immune Targeted Therapies for Depression: Antidepressant Effects of Monoclonal Antibodies
June 24, 2024
Immune dysregulation may contribute to treatment resistance in depression. Monoclonal antibodies have shown promise in treating depression when used for inflammatory disorders and may offer new hope for patients…
Original Research
Depression, Rumination, and Suicide Attempts in Adolescents With Mood Disorders: Sex Differences
June 19, 2024
The authors found that in male adolescents, suicide attempts are mostly influenced by depressive symptoms. In female adolescents, depressive symptoms not only directly increase the risk of suicide attempts,…