The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
Manifestations Associated With CNS Lesions
Rounds in the General Hospital

May 19, 2026

Neuropsychiatric manifestations of brain metastases are varied, although certain symptoms can be associated with the brain region in which there is a metastasis; lesions that affect certain parts of…
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PCC
Adjunct Memantine for Inappropriate Sexual Behavior
Case Report

May 14, 2026

Two patients with intellectual disability and major neurocognitive disorder exhibited inappropriate sexual behavior that significantly decreased after memantine was added as adjunctive therapy.
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PCC
From Physical to Digital: Hoarding Phenomena in Obsessive-Compulsive Disorder
Case Report

May 14, 2026

This case illustrates how hoarding phenomenology can manifest in digital environments, which offer virtually unlimited storage, anonymity, and low visibility.
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PCC
Differentiating Bipolar and Other Psychiatric Disorders
Rounds in the General Hospital

May 12, 2026

Diagnosis of bipolar spectrum disorder is often complicated, as most patients present for care during depressive episodes, which are more frequent than hypomanic or manic episodes.
, , , et al
PCC
Aripiprazole-Induced Pathological Gambling
Case Report

May 7, 2026

A 27-year-old man with a history of substance abuse developed a new-onset compulsive gambling pattern within weeks of starting aripiprazole.
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PCC
Strategies for Documenting the Medical Record
Rounds in the General Hospital

May 7, 2026

Documentation should be objective and relevant, especially in psychosocially complex cases—too much information can interfere with establishing the correct diagnosis and treatment plan, while too little increases risk of…
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PCC
Readability of Self-Reported Psychosis Measures
Original Research

May 5, 2026

Most psychosis self-report measures are written above recommended reading levels, reducing accessibility for many patients with cognitive, educational, or symptomatic limitations.
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PCC
Clozapine-Associated Pulmonary Embolism
Case Report

May 5, 2026

A 48-year-old woman with schizoaffective disorder taking clozapine developed acute pulmonary embolism despite negative D-dimer results.
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PCC
Polydipsia-Related Hyponatremia in Autism
Case Report

April 30, 2026

The authors present the case of a 10-year-old boy with autism who presented to the ED with hyponatremia-related seizures due to compulsive water drinking.
, , , et al
PCC
Diphenhydramine and Dextromethorphan Overdose
Case Report

April 28, 2026

The authors describe a case of intentional overdose with diphenhydramine and extended-release dextromethorphan-guaifenesin that initially presented with anticholinergic toxicity and later evolved into serotonin toxicity.
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PCC
Antidepressant Monitoring Referrals to Higher-Level Services
Original Research

April 23, 2026

This study examined predictors of referral from a collaborative care model antidepressant monitoring program to higher levels of psychiatric services.
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PCC
Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome
Case Report

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.
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