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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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Rounds in the General Hospital

PCC
Clozapine: Its Use and Monitoring
Rounds in the General Hospital

July 30, 2024

The authors provide the latest information on clozapine use, including when your patients should receive or avoid taking it, what laboratory tests are required before and during administration, and…
Desta S. Lissanu, Chirag M. Vyas, Carol S. Lim, et al
PCC
Pharmacologic Management of TBI
Rounds in the General Hospital

July 16, 2024

Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on…
Sofia E. Matta, Christina LaCroix, Kaloyan Tanev, et al
PCC
Evaluation and Management of Treatment-Resistant Schizophrenia
Rounds in the General Hospital

July 2, 2024

If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette…
Carol S. Lim, Abigail L. Donovan, Chirag M. Vyas, et al
PCC
Neuropsychiatric Complications of Hypervitaminosis D
Rounds in the General Hospital

June 13, 2024

A 28-year-old man presented to the emergency department with severe agitation, insomnia, weakness, constipation, and muscle jerks after nonsuicidal overdosing of vitamin D.
James K. Rustad, Adam Z. Spitz, Brandon C. Wilson, et al
PCC
Impact of Disability on Medical Care
Rounds in the General Hospital

June 6, 2024

Given that many people have disabilities, physicians should develop skills that assess the level of disability, the functional consequence of illness, and the social and physical environments of patients…
Mirza Baig, Andrew S. Chun, Ashika Bains, et al
PCC
Management of Rumination and Obsessions in Primary Care
Rounds in the General Hospital

May 30, 2024

Difficult-to-control negative repetitive thoughts can manifest as ruminations or obsessions. Appropriate early identification and intervention can positively affect the course and prevent an episode of psychiatric illness.
Sharmin Ghaznavi, Charlotte Schiewe, Theodore A. Stern

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More PCC Articles

JCP
Commentary

January 18, 2022

This commentary discusses the article by Zeifman and colleagues on the role classic psychedelic agents may have in reducing risk of suicide.
Daniel H. Grossman, Peter S. Hendricks
JCP
Meta-Analysis

January 18, 2022

Psychedelic therapy shows promise for a range of mental health concerns, including suicidality. This meta-analysis is the first to systematically examine the effects of psychedelic therapy on suicidality.
Richard J. Zeifman, Dengdeng Yu, Nikhita Singhal, et al
JCP
Meta-Analysis

January 18, 2022

Repetitive magnetic transcranial stimulation (rTMS) has been established as an efficacious treatment for MDD. This meta-analysis looked at its effects on suicidal ideation in depressed patients across the lifespan.
Shobha Mehta, Gerasimos Konstantinou, Cory R. Weissman, et al
JCP
Original Research

January 11, 2022

Increasing evidence has indicated a relationship between depression and diabetes mellitus (DM). This study investigated differences in suicide and all-cause mortality from comorbid major depression and type 2 DM…
Chun-Jen Huang, Yu-Ting Huang, Pai-Cheng Lin, et al
JCP
Editorial

January 11, 2022

Editor-in-Chief Marlene P. Freeman reflects on the past year and expresses gratitude for JCP’s authors, peer reviewers, and staff.
Marlene P. Freeman
JCP
Original Research

January 11, 2022

Current practices for estimating the risk for mortality in teenage substance users rely heavily on clinical intuition. This study examined whether a positive urine drug screen in youth receiving…
Matej Markota, Paul E. Croarkin, William V. Bobo
JCP
Commentary

January 4, 2022

This commentary discusses the review by Vaccarino and colleagues of cognitive effects associated with ketamine treatment for major depressive disorder.
Joseph F. Goldberg
JCP
Systematic Review

January 4, 2022

The cognitive effects of ketamine have not been thoroughly investigated in depressed populations. This systematic review sought to determine the objective neurocognitive effects of ketamine in individuals with unipolar…
Sophie R. Vaccarino, Fathima Adamsahib, Roumen V. Milev, et al
JCP
Original Research

January 4, 2022

Are injuries before age 5 early manifestations of ADHD? And do genetics play a role? This study drew on a large Danish database to investigate these questions.
Theresa Wimberley, Isabell Brikell, Emil M. Pedersen, et al
JCP
In Memoriam

January 4, 2022

Aaron T. Beck, founding father of Cognitive Therapy, was ranked the fourth most influential person in the history of medicine in a 2016 survey. Colleague and friend Michael Thase…
Michael E. Thase
JCP
Meta-Analysis

December 28, 2021

This review synthesizes evidence on the efficacy of motivational interviewing in reducing substance use and psychotic symptoms.
Wenyue Wang, Anson Kai Chun Chau, Paul Kong, et al
JCP
Original Research

December 28, 2021

Data on adherence to antipsychotics are typically from clinical trials. This study is the first to compare persistence and adherence between paliperidone palmitate once-monthly injection and oral antipsychotics in…
Huaning Wang, Yongjing Zhang, Jin Liu, et al

Celebrating
85 Years

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