The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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PCC
Complex Long-Term Catatonia
Case Report

Complex Long-Term Catatonia

November 2, 2023

This is a case of an inpatient with catatonic schizophrenia with multiple systemic repercussions and complex etiology.
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PCC
Xylazine as a Fentanyl Adulterant in the US
Narrative Review

Xylazine as a Fentanyl Adulterant in the US

October 31, 2023

Data obtained from studies between 2006 and 2022 indicate a rapidly increasing incidence of xylazine overdose in the United States, with overdose cases now being seen in 25 states.
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PCC
Leukoencephalopathy After Excessive Cannabinoid Use
Case Report

Leukoencephalopathy After Excessive Cannabinoid Use

October 31, 2023

This is a case of a male patient with diffused signal and spongiform changes in the brain due to cannabis use.
, , , et al
PCC
Rapid Treatment of Anhedonia With Pramipexole as Adjunct to Buprenorphine in OUD
Case Report

Rapid Treatment of Anhedonia With Pramipexole as Adjunct to Buprenorphine in OUD

October 26, 2023

In this case, pramipexole rapidly improved depression and anhedonia symptoms in a patient on buprenorphine and an antidepressant.
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PCC
Auditory Hallucinations Induced by Hyponatremia
Case Report

Auditory Hallucinations Induced by Hyponatremia

October 24, 2023

An elderly woman with no past or family history of psychiatric illness presented with well-formed auditory hallucinations in the setting of profound hyponatremia.
, , , et al
PCC
[RETRACTED] Body Dysmorphia, Steroid Use, and Mental Health
Systematic Review

[RETRACTED] Body Dysmorphia, Steroid Use, and Mental Health

October 24, 2023

Steroid use is associated with many detrimental effects on mental health, including a higher risk of developing symptoms of psychosis, depression, anxiety, and aggression.
, , , et al
PCC
Topiramate for Civilian PTSD
Original Research

Topiramate for Civilian PTSD

October 19, 2023

The results for anticonvulsants in the treatment of PTSD have been mixed. This study investigated the efficacy and safety of the anticonvulsant agent topiramate for the treatment of civilian…
, , , et al
PCC
Association of Khat Use Disorder and Antisocial Personality Disorder Among Inmates
Original Research

Association of Khat Use Disorder and Antisocial Personality Disorder Among Inmates

October 17, 2023

This study examined the relationship between khat use disorder and antisocial personality disorder in newly admitted inmates in a correctional facility in Ethiopia.
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PCC
Visual and Auditory Hallucinations in Anxious Preadolescent Children
Case Report

Visual and Auditory Hallucinations in Anxious Preadolescent Children

October 17, 2023

This is the case of a 10-year-old boy with auditory and visual hallucinations in the context of long-standing anxiety, highlighting a unique phenomenon wherein symptoms persisted for years.
PCC
COVID-19–Induced Mania
Case Report

COVID-19–Induced Mania

October 12, 2023

A 54-year-old man recently infected with COVID-19 was brought to the ED by police with new-onset mania. He had no significant medical or psychiatric history.
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PCC
Cognition in Schizophrenia
Systematic Review

Cognition in Schizophrenia

October 12, 2023

This systematic review showed specific cognitive functioning in individuals diagnosed with schizophrenia, highlighting lower than average performance compared to healthy controls regarding executive cognitive functions such as information processing,…
, , , et al
PCC
Rathke’s Cleft Cyst and Psychiatric Symptoms in an Adolescent
Case Report

Rathke’s Cleft Cyst and Psychiatric Symptoms in an Adolescent

October 10, 2023

An adolescent male with Rathke’s cleft cyst has experienced anxiety, psychosis, OCD, and ADHD.
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