Thyroid Augmentation of Mirtazapine: A Case Report

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Depression is a common but debilitating illness in theUnited States with a prevalence rate ranging from 4.8% to 9.2%in primary care practice.¹ Fortunately, there are many antidepressantmedications to treat patients with depression. However,up to 46% of patients treated with antidepressants do notadequately respond to treatment.² A smaller number 5% to10% will continue to experience depression despite numeroustherapeutic interventions.³ Clinicians are then left to treat thesepatients who do not experience a full response using a numberof treatment options.